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SLEEP RESEARCH

ID 149: NEUROMODULATION-OSA. Brain stimulation to enhance slow brain waves in obstructive sleep apnea

About the study

People with obstructive sleep apnea (OSA) show impairments in memory and attention and are at risk for developing dementia. Slow wave brain waves, occurring during “deep sleep”, have been associated with memory and attention and are less prominent in people with sleep apnea. This research study aims to understand whether low current brain stimulation applied on different areas can boost slow brain waves during sleep in people with obstructive sleep apnea.

What's involved

The screening procedures for this study include:
* a phone call from the research coordinator, online screening questionnaires (10-15 mins),
* medical screening over the phone (15-20 mins).

You will be asked to wear a watch to monitor your sleep (3 weeks at home).

The visits to the Woolcock will include memory and attention testing before and after a nap with low intensity brain stimulation applied during sleep.

Visits required

This study involves 3 in-person daytime visits to the Woolcock Institute of Medical Research.

Eligibility criteria

  • Aged 40-65 years
  • Have moderate to severe obstructive sleep apnea (OSA)
  • Fluent in English
  • Able to perform cognitive tasks
  • Have not used treatment for obstructive sleep apnea (OSA) in the last 2 months

Chief investigator: Dr Angela D'Rozario

Ethics approvals:

This study has been approved by the Sydney Local Health District- RPAH HREC (number 2024/ETH00185) which is a registered human ethics committee in accordance with the National Statement on Ethical Conduct of Human Research (2007) incorporating all updates.

Find out more

Contact: Andrea Ricciardiello

Call: 02 9805 3289

Email: andrea.ricciardiello@woolcock.org.au